http://scholars.ntou.edu.tw/handle/123456789/21323
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gopalakrishnan Vinoj | en_US |
dc.contributor.author | Rengarajan Jayakumar | en_US |
dc.contributor.author | Jiann-Chu Chen | en_US |
dc.contributor.author | Boonsirm Withyachumnarnkul | en_US |
dc.contributor.author | Sathappan Shanthi | en_US |
dc.contributor.author | Baskaralingam Vaseeharan | en_US |
dc.date.accessioned | 2022-03-30T01:22:39Z | - |
dc.date.available | 2022-03-30T01:22:39Z | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 1050-4648 | - |
dc.identifier.uri | http://scholars.ntou.edu.tw/handle/123456789/21323 | - |
dc.description.abstract | Four strains of N-hexanoyl-L-homoserine lactone (AHL)-degrading Pseudomonas spp., named PsDAHP1, PsDAHP2, PsDAHP3, and PsDAHP4 were isolated and identified from the intestine of Fenneropenaeus indicus. PsDAHP1 showed the highest AHL-degrading activity among the four isolates. PsDAHP1 inhibited biofilm-forming exopolysaccharide and altered cell surface hydrophobicity of virulent green fluorescent protein (GFP)-tagged Vibrio parahaemolyticus DAHV2 (GFP-VpDAHV2). Oral administration of PsDAHP1 significantly reduced zebrafish mortality caused by GFP-VpDAHV2 challenge, and inhibited colonisation of GFP-VpDAHV2 in the gills and intestine of zebrafish as evidence by confocal laser scanning microscope and selective plating. Furthermore, zebrafish receiving PsDAHP1-containing feed had increased phagocytic cells of its leucocytes, increased serum activities of superoxide dismutase and lysozyme. The results suggest that Pseudomonas aeruginosa PsDAHP1 could protect zebrafish from V. parahaemolyticus infection by inhibiting biofilm formation and enhancing defence mechanisms of the fish. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ELSEVIER | en_US |
dc.relation.ispartof | FISH & SHELLFISH IMMUNOLOGY | en_US |
dc.subject | INNATE IMMUNE-RESPONSES | en_US |
dc.subject | BIOFILM FORMATION | en_US |
dc.subject | EXOPOLYSACCHARIDE PRODUCTION | en_US |
dc.subject | EPINEPHELUS-COIOIDES | en_US |
dc.subject | AEROMONAS-HYDROPHILA | en_US |
dc.subject | COLONY MORPHOLOGY | en_US |
dc.subject | SIGNAL MOLECULES | en_US |
dc.subject | LUXRI HOMOLOGS | en_US |
dc.subject | QUORUM | en_US |
dc.subject | AQUACULTURE | en_US |
dc.title | N-hexanoyl-L-homoserine lactone-degrading Pseudomonas aeruginosa PsDAHP1 protects zebrafish against Vibrio parahaemolyticus infection | en_US |
dc.type | journal article | en_US |
dc.identifier.doi | 10.1016/j.fsi.2014.10.033 | - |
dc.identifier.isi | WOS:000348015700025 | - |
dc.relation.journalvolume | 42 | en_US |
dc.relation.journalissue | 1 | en_US |
dc.relation.pages | 204-212 | en_US |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | no fulltext | - |
item.languageiso639-1 | en_US | - |
crisitem.author.dept | Department of Aquaculture | - |
crisitem.author.dept | College of Life Sciences | - |
crisitem.author.dept | National Taiwan Ocean University,NTOU | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
Appears in Collections: | 水產養殖學系 |
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