http://scholars.ntou.edu.tw/handle/123456789/22014
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chang, Aiping | en_US |
dc.contributor.author | Ye, Zeli | en_US |
dc.contributor.author | Ye, Zhenquan | en_US |
dc.contributor.author | Deng, Jinfeng | en_US |
dc.contributor.author | Lin, Jieying | en_US |
dc.contributor.author | Wu, Changjer | en_US |
dc.contributor.author | Zhu, Hu | en_US |
dc.date.accessioned | 2022-07-01T01:53:05Z | - |
dc.date.available | 2022-07-01T01:53:05Z | - |
dc.date.issued | 2022-09-01 | - |
dc.identifier.issn | 0144-8617 | - |
dc.identifier.uri | http://scholars.ntou.edu.tw/handle/123456789/22014 | - |
dc.description.abstract | Sphingan WL gum (WL), a kind of exopolysaccharides, is produced by Sphingomonas sp. WG. In this study, citric acid (CA) crosslinked WL hydrogel films were firstly developed for potential wound dressing application. ATRFTIR and TG results suggested the occurrence of esterification crosslinking. SEM analysis showed that this aided covalent crosslinking could prevent their porous structures from collapsing when swelling. Due to the deprotonation of carboxyl groups, the water absorption capacity of WL-CA hydrogel films increased with the increase of pH (maximum swelling ratio = 38 g/g). The covalent crosslinked swollen WL-CA hydrogels exhibited certain hydrolytic stability, high porosity (> 60%), moderate tissue adhesion, and good rheological property (G ' > G '', G ' up to 2 kPa). WL-CA-CIP hydrogel films loaded with antibiotic ciprofloxacin (CIP) showed sustained drug release properties, long-lasting antibacterial activity, and superior biocompatibility. All the results indicated that WLbased hydrogels were potential candidates for wound dressing applications. | en_US |
dc.language.iso | English | en_US |
dc.publisher | ELSEVIER SCI LTD | en_US |
dc.relation.ispartof | CARBOHYDRATE POLYMERS | en_US |
dc.subject | Sphingan WL gum | en_US |
dc.subject | Exopolysaccharide | en_US |
dc.subject | Hydrogel dressing | en_US |
dc.subject | Antibacterial activity | en_US |
dc.subject | pH-responsive | en_US |
dc.title | Citric acid crosslinked sphingan WL gum hydrogel films supported ciprofloxacin for potential wound dressing application | en_US |
dc.type | journal article | en_US |
dc.identifier.doi | 10.1016/j.carbpol.2022.119520 | - |
dc.identifier.isi | WOS:000799067800003 | - |
dc.relation.journalvolume | 291 | en_US |
dc.identifier.eissn | 1879-1344 | - |
item.fulltext | no fulltext | - |
item.languageiso639-1 | English | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | College of Life Sciences | - |
crisitem.author.dept | Department of Food Science | - |
crisitem.author.dept | National Taiwan Ocean University,NTOU | - |
crisitem.author.dept | Institute of Food Safety and Risk Management | - |
crisitem.author.dept | Bachelor Degree Program in Marine Biotechnology | - |
crisitem.author.dept | Center of Excellence for the Oceans | - |
crisitem.author.dept | Doctoral Degree Program in Marine Biotechnology | - |
crisitem.author.dept | Master Program of Food Satfety Management | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | College of Life Sciences | - |
顯示於: | 食品科學系 |
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