http://scholars.ntou.edu.tw/handle/123456789/5471
標題: | A comparison of immunohistochemical and molecular methods used for analyzing the BRAF V600E gene mutation in malignant melanoma in Taiwan |
作者: | Huang, Wen-Kuan Kuo, Tseng-Tong Wu, Chiao-En Cheng, Hsin-Yi Hsieh, Chia-Hsun Hsieh, Jia-Juan Shen, Yung-Chi Hou, Ming-Mo Hsu, Todd Chang, John Wen-Cheng |
關鍵字: | METASTATIC MELANOMA;MONOCLONAL-ANTIBODY;THYROID-CARCINOMA;FEATURES;VEMURAFENIB;PREVALENCE;EXPRESSION;CANCER;NRAS |
公開日期: | 十二月-2016 |
出版社: | WILEY |
卷: | 12 |
期: | 4 |
起(迄)頁: | 403-408 |
來源出版物: | ASIA-PAC J CLIN ONCO |
摘要: | Aims: The BRAF V600 mutation has been shown to be clinically meaningful in terms of both the prognosis and sensitivity of BRAF inhibitors in patients with metastatic melanoma. Recently, a BRAF V600E mutation-specific antibody, VE1, was generated for the detection of tumors bearing BRAF V600E mutations. To determine the clinical value of immunohistochemical testing, we compared the prevalence of mu... |
URI: | http://scholars.ntou.edu.tw/handle/123456789/5471 |
ISSN: | 1743-7555 |
DOI: | 10.1111/ajco.12574 |
顯示於: | 生命科學暨生物科技學系 03 GOOD HEALTH AND WELL-BEING |
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