http://scholars.ntou.edu.tw/handle/123456789/5610
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lee, Yen-Fei | en_US |
dc.contributor.author | Deng, Ting-Wei | en_US |
dc.contributor.author | Chiu, Wei-Jane | en_US |
dc.contributor.author | Wei, Tsao-Yen | en_US |
dc.contributor.author | Roy, Prathik | en_US |
dc.contributor.author | Huang, Chih-Ching | en_US |
dc.date.accessioned | 2020-11-19T10:39:57Z | - |
dc.date.available | 2020-11-19T10:39:57Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0003-2654 | - |
dc.identifier.uri | http://scholars.ntou.edu.tw/handle/123456789/5610 | - |
dc.description.abstract | We have developed a simple, low-cost, paper-based probe for the selective colorimetric detection of copper ions (Cu2+) in aqueous solutions. The bovine serum albumin (BSA)-modified 13.3-nm Au nanoparticle (BSA-Au NP) probe was designed to detect Cu2+ ions using lead ions (Pb2+) and 2-mercaptoethanol (2-ME) as leaching agents in a glycine-NaOH (pH 12.0) solution. In addition, a nitrocellulose membrane (NCM) was used to trap the BSA-Au NPs, leading to the preparation of a nanocomposite film consisting of a BSA-Au NP-decorated membrane (BSA-Au NPs/NCM). The BSA-Au NPs probe operates on the principle that Cu deposition on the surface of the BSA-Au NPs inhibits their leaching ability, which is accelerated by Pb2+ ions in the presence of 2-ME. Under optimal solution conditions (5 mM glycine-NaOH (pH 12.0), Pb2+ (50 mu M), and 2-ME (1.0 M)), the Pb2+/2-ME-BSA-Au NPs/NCM enabled the detection of Cu2+ at nanomolar concentrations in aqueous solutions by the naked eye with high selectivity (at least 100-fold over other metal ions). In addition, this cost-effective probe allowed for the rapid and simple determination of Cu2+ ions in not only natural water samples but also in a complex biological sample (in this case, blood sample). | en_US |
dc.language.iso | en_US | en_US |
dc.relation.ispartof | Analyst | en_US |
dc.subject | ATOMIC-ABSORPTION-SPECTROMETRY | en_US |
dc.subject | COLORIMETRIC CU2+ DETECTION | en_US |
dc.subject | SERUM COPPER | en_US |
dc.subject | LEAD IONS | en_US |
dc.subject | FLUORESCENT SENSORS | en_US |
dc.subject | MASS-SPECTROMETRY | en_US |
dc.subject | OPTICAL-DETECTION | en_US |
dc.subject | HIGH-SENSITIVITY | en_US |
dc.subject | AQUEOUS-SOLUTION | en_US |
dc.subject | SILVER NANODOTS | en_US |
dc.title | Visual detection of copper(II) ions in blood samples by controlling the leaching of protein-capped gold nanoparticles | en_US |
dc.type | journal article | en_US |
dc.identifier.doi | 10.1039/c2an16270a | - |
dc.identifier.isi | WOS:000301674600009 | - |
dc.relation.journalvolume | 137 | en_US |
dc.relation.journalissue | 8 | en_US |
dc.relation.pages | 1800-1806 | en_US |
item.languageiso639-1 | en_US | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
crisitem.author.dept | College of Life Sciences | - |
crisitem.author.dept | Department of Bioscience and Biotechnology | - |
crisitem.author.dept | National Taiwan Ocean University,NTOU | - |
crisitem.author.dept | Center of Excellence for the Oceans | - |
crisitem.author.orcid | 0000-0002-0363-1129 | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
顯示於: | 生命科學暨生物科技學系 |
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