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  1. National Taiwan Ocean University Research Hub

Isolation and Identification of Bioactive Glycolipids and Cyclic Peptide from Shellfish (I)

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Project title
Isolation and Identification of Bioactive Glycolipids and Cyclic Peptide from Shellfish (I)
Code/計畫編號
NSC92-2321-B019-005
Translated Name/計畫中文名
台灣養殖貝類生理活性物質的分離鑑定與功能評估(一)蜆(二)文蛤(三)牡蠣---貝類具生理活性脂多醣與Cyclic peptides 之分離純化及鑑定(I)
 
Project Coordinator/計畫主持人
Yeuk-Chuen Liu
Funding Organization/主管機關
National Science and Technology Council
 
Department/Unit
Department of Food Science
Website
https://www.grb.gov.tw/search/planDetail?id=923385
Year
2003
 
Start date/計畫起
01-08-2003
Expected Completion/計畫迄
01-07-2004
 
Bugetid/研究經費
630千元
 
ResearchField/研究領域
食品科技(農)
漁業
 

Description

Abstract
前期研究發現以花蓮產的黃金蜆先以MeOH 萃取後再以EA/H2O 進 行分層萃取(FC-Me-EA) 後,發現FC-Me-EA可顯著的造成人類肝癌 細胞(Hep-J2 及Hep-G2 cell)的凋亡。因此本研究集中採甲醇萃取後經 乙酸乙酯分層的樣品(FC-Me-EA),進行分離純化,以利具活性化合 物的分析鑑定。 因為前期研究發現以花蓮產的黃金蜆的粗分離物具顯著的抗癌作 用,本階段研究擬集中分離純化黃金蜆的有效成份。(圖
 
 
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