食品製造業中微生物之背景值調查研究

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基本資料

Project title

食品製造業中微生物之背景值調查研究

Code/計畫編號

MOHW111-FDA-F-114-000374

Translated Name/計畫中文名

食品製造業中微生物之背景值調查研究

Project Coordinator/計畫主持人

Hong-Ting Lin

Funding Organization/主管機關

Food and Drug Administration, MOHW

Department/Unit

Department of Food Science

Website

https://www.grb.gov.tw/search/planDetail?id=14191369

Year

2022

Start date/計畫起

01-01-2022

Expected Completion/計畫迄

31-12-2022

Bugetid/研究經費

1211.2千元

ResearchField/研究領域

食品科技(農)

抗生素的抗藥性被世界衛生組織列為目前全球在人類健康及食品安全上最大的挑戰之一。抗生素抗藥性影響的層面相當深遠，從各國家至各年齡層的人類都可能受到影響。除了可能導致更長的住院時間及更高的醫療費用，也可能伴隨著更高的死亡率。美國疾病管制與預防中心指出食品及動物是人類接觸抗藥性微生物的主要來源之一，而加強大眾及食品相關從業人員對抗藥性食源性微生物的認知為一個有效防治抗藥性食源性微生物的途徑。然而，國內針對抗藥性食源性病原菌的研究仍然不足，食品及食品相關從業人員取得抗藥性病原菌相關知識的管道缺乏，為了有效防治抗藥性病原菌的問題，宜推廣相關知識及擬定防治長期策略，從建立臺灣抗藥性食源性微生物的科學可靠研究數據，加強食品相關從業人員的基本認知及防護策略，以減少抗藥性病原菌對臺灣民眾及環境的風險及負擔。本計畫參考衛福部食藥署109及110先期計畫研究成果，擬至雞肉食品製造業，採樣食品及其接觸器具樣品 (含生物膜)共36件，進行微生物菌叢分析，預計分離鑑定微生物菌種含大腸桿菌共8種，並針對12種抗生素進行抗藥性分析。並召開2次專家會議針對採樣規劃，抗藥性微生物監測及分析及「食媒性抗藥性微生物之管理政策」草案做出討論。此外，撰寫食品製造業中抗藥性微生物之管理為主題的知識文章、及投稿國內外論文草案1篇，並完成年度研究成果報告。 Antibiotic resistance is recognized by the World Health Organization as one of the biggest challenges to human health and food safety in the world. The impact of antibiotic resistance is far-reaching, and humans at all ages from all countries may be affected. In addition to longer hospitalization and higher medical costs, antibiotic resistance may cause higher mortality. The U.S. Centers for Disease Control and Prevention pointed out that food and animals are one of the main sources of human exposure to drug-resistant microorganisms. To enhance the public and food industry employees’ awareness of drug-resistant food-borne microorganisms is an effective way to prevent and control drug-resistant food-borne microorganisms. However, domestic research on drug-resistant food-borne pathogens is still insufficient, and food industry employees lack access to knowledge about drug-resistant pathogens. In order to effectively prevent and control drug-resistant pathogens, relevant knowledge should be promoted and long-term strategies should be formulated. From the establishment of scientific and reliable research data on drug-resistant food-borne microorganisms in Taiwan, the basic cognition and protection strategies of food-related practitioners are strengthened to reduce the risk and burden of drug-resistant pathogens to Taiwanese people and the environment. By referring to the research results of the 2019 and 2020 projects of the Food and Drug Administration of the Ministry of Health and Welfare, we planned to go to chicken food manufacturing industries for a sampling of 36 food and its contact equipment (including biofilms). The samples will be investigated for microbial flora analysis, and eight target microorganisms including E. coli will be isolated and identified. The drug resistance analysis is carried out for 12 kinds of antibiotics. Two expert meetings will be held to discuss sampling plans, monitoring and analysis of drug-resistant microorganisms, and the draft of "management policy for food-borne drug-resistant microorganisms". In addition, a popular science article on the management of drug-resistant microorganisms in the food manufacturing industry will be written, a draft manuscript for submitting to a domestic and foreign journal will be constructed, and the annual research results report will be completed.

Keyword(s)

食品
食品從業人員
微生物抗藥性
風險分級矩陣
次世代定序
微生物菌叢
Food
Food industry employees
microbial drug resistance
Risk ranking matrix
Next Generation Sequencing
Microbiota

DSpace CRIS

食品製造業中微生物之背景值調查研究

基本資料

Description