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  1. National Taiwan Ocean University Research Hub

Biochemical Studies of Polyamine Synthases from Diatom, and Their Applications in Synthetic Biology(II)

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Project title
Biochemical Studies of Polyamine Synthases from Diatom, and Their Applications in Synthetic Biology(II)
Code/計畫編號
MOST110-2313-B019-003-MY3
Translated Name/計畫中文名
矽藻特殊多胺合成酶與多胺代謝途徑的研究與應用(II)
 
Project Coordinator/計畫主持人
Han-Jia Lin
Funding Organization/主管機關
National Science and Technology Council
 
Department/Unit
Department of Bioscience and Biotechnology
Website
https://www.grb.gov.tw/search/planDetail?id=13901642
Year
2021
 
Start date/計畫起
01-08-2021
Expected Completion/計畫迄
31-07-2022
 
Bugetid/研究經費
1700千元
 
ResearchField/研究領域
漁業
 

Description

Abstract
本研究發現海洋矽藻能合成一種長鏈多胺 HCPA,此成分具有抗病毒與抗氧化等產業應用潛力。因此擬先研究矽藻合成 HCPA 的酵素與代謝途徑,然後以合成生物學的概念,改造大腸桿菌大量生產 HCPA。本計劃不論在基礎研究與產業應用性兩方面 都非常有趣,而且已經有相當可靠的初期成果證實可行性。未來有機會從計畫成果 衍生出實際在產業利用的產品。
 
Keyword(s)
矽藻
長鏈多胺
代謝組
胺丙基轉移酶
合成生物學
Diatom
long chain polyamine
metabolon
aminopropyl transferase
synthetic biology
 
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