http://scholars.ntou.edu.tw/handle/123456789/17819
標題: | Electrocatalytic CuBr@CuO nanoparticles based salivary glucose probes | 作者: | Lin, Wei-Jan Lin, Yu-Syuan Chang, Huan-Tsung Unnikrishnan, Binesh Huang, Chih-Ching |
關鍵字: | CANDIDAL CARRIAGE;ELECTRODEPOSITION;PHOTOCATALYST;REDUCTION;BIOSENSOR;OXIDATION;CATALYSTS;INSIGHT;SENSOR | 公開日期: | 15-十二月-2021 | 出版社: | ELSEVIER ADVANCED TECHNOLOGY | 卷: | 194 | 來源出版物: | BIOSENS BIOELECTRON | 摘要: | Highly electrocatalytic cuprous halide/copper oxide nanoparticles (CuX@CunO NPs; X = Cl, Br or I; n = 1 or 2) have been fabricated on copper foils for sensitive detection of glucose. Formation of CuX@CunO NPs involves two steps- in situ electrochemical deposition of CuX on the foil and then conversion of CuX to CunO. The deposited CuX converts to CunO, leading to the generation of abundant oxygen vacancies in the CuO lattice, enhancing the number of catalytically active sites, and improving the charge transfer efficiency. Among the asprepared electrodes, CuBr@CuO NP ones provide the highest electrocatalytic activity toward the oxidation of glucose. The electrode provides electrocatalytic activity toward the oxidation of glucose at a low overpotential of 0.25 V (vs. SCE), which is lower than that (0.40 V) of unmodified copper electrodes. The generated anodic current is proportional to glucose concentration in an alkaline medium, with a good linear range from 5.0 mu M to 3.51 mM (R2 = 0.995). Its reliability has been validated by detecting the glucose concentration in saliva samples at different time intervals after a meal. The results are in good correlation with the blood glucose level determined by using a commercial blood glucose meter. Our CuBr@CuO NP electrode possesses great potential for monitoring salivary glucose to achieve the purpose of noninvasive glucose monitoring for patients with diabetes in the future. |
URI: | http://scholars.ntou.edu.tw/handle/123456789/17819 | ISSN: | 0956-5663 | DOI: | 10.1016/j.bios.2021.113610 |
顯示於: | 生命科學暨生物科技學系 03 GOOD HEALTH AND WELL-BEING |
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