Development of Nanosized Marine Neutraceutical Products

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Project title

Code/計畫編號

94農科-12.1.1-漁-F1(3)

Translated Name/計畫中文名

海洋生技食品奈米生產化技術之研發

Project Coordinator/計畫主持人

Ke-Liang Chang

Funding Organization/主管機關

Council of Agriculture,Executive Yuan

Co-Investigator(s)/共同執行人

龔瑞林

Department/Unit

Department of Food Science

Website

https://www.grb.gov.tw/search/planDetail?id=1157210

Year

2005

Start date/計畫起

01-01-2005

Expected Completion/計畫迄

01-12-2005

Co-Investigator(s)

Zwe-Ling Kong

Bugetid/研究經費

500千元

ResearchField/研究領域

食品科技(農)

海洋生物含有許多保健成份，例如文蛤有保肝功能、藻類有抗腫瘤機能。牛磺酸具有減少心律不整、降血壓及調節血中膽固醇等功用。Glutathione有抗氧化、解毒及免疫調節功能。水產生物中還有更多生物活性成份有待發掘。如果開發新穎的水產保健食品，將可提高國內水產品的附加價值。運用奈米科技結合生物技術產品是極有潛力的領域。然而大量製備及各種性能的分析檢驗等方面仍有很多有待解決的問題。本計畫在本年度內擬以本土性海洋生物原料中之藻類多醣及含有機能性之蛋白質萃取物或水解物，配合幾丁聚醣與褐藻酸鈉開發高經濟價值之微奈米海洋生技保健食品，探討最適的萃取分離方法及分析步驟，並建立以細胞模式做為快速篩選活性物質及評估奈米化產品效益之方法。本計畫之執行預期可協助提升國內之海洋奈米生物技術，更可提供國內海洋生技保健食品產業未來新產品開發有用之參考資訊。 It is well known that the marine environment provides a rich source of extremely potent compounds that have demonstrated significant activities in nutraceutical, antitumor, immunomodulation, allergy, or anti-viral assays. For instance, clam extract is beneficial to the liver function. Some algal compounds have antitumor property. Taurine can improve the health status of the cardiovascular system and blood cholesterol level. Many more bioactive compounds wait to be explored and utilized. The development of novel marine nutraceuticals would help create many more value-added marine food products. The integration of nanotechnology and biotechnology has a great potential in the future. However, many problems remain to be resolved. In this study, we propose to develop the method of making nanoparticles from marine polysaccharides and functional extract or hydrolysate of algae and proteins of marine origin. Glutathione, fish protein hydrolysate, alginate, and chitosan will be used as the raw materials. We will investigate the optimal conditions for isolating the bioactive compounds from marine organisms. The analytical procedure for the bioactive compounds will be established. In addition, a cell-based bioassay will be applied to evaluate both the bioactive properties of raw materials and their nanoparticles. The implementation of this project will help develop nanoparticles of marine nutraceuticals. The results will help advance the marine nanobiotechnology in Taiwan. They will also provide useful information for the new product development in local marine health food industry.

Keyword(s)

龍鬚菜
幾丁聚醣
褐藻酸鹽
奈米粒
肽類
Chitosan
Alginate
Nanoparticle
Peptide
Gracilaria

DSpace CRIS

Development of Nanosized Marine Neutraceutical Products

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