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  1. National Taiwan Ocean University Research Hub

Marine Featured Drug Delivery System Combined with Quadruple Therapy

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Details

Project title
Marine Featured Drug Delivery System Combined with Quadruple Therapy
Code/計畫編號
110-2113-M-019-006-
Translated Name/計畫中文名
四重結合治療之具有海洋特色的藥物遞送系統
 
Project Coordinator/計畫主持人
Hsiu-Mei Lin
Funding Organization/主管機關
National Science and Technology Council
 
Department/Unit
Department of Bioscience and Biotechnology
Website
https://www.grb.gov.tw/search/planDetail?id=13895685
Year
2021
 
Start date/計畫起
01-08-2021
Expected Completion/計畫迄
31-07-2022
 
Bugetid/研究經費
900千元
 
ResearchField/研究領域
化學
 

Description

Abstract
本計畫是結合光動力、光熱、磁熱與化療治療及溫度控制釋放的藥物傳遞系統,藉由光熱或磁熱特性的奈米粒子標靶出癌組織後接著照射光源或交變磁場,即能在局部產生高溫,使癌細胞凋亡,並且在治療過程中所產生的溫度變化將被利用於溫度控制釋放藥物系統。推展綠色化學的觀念,因此使用矽藻土當作奈米藥物載體的材料,最後想藉由結合治療的方法、溫度控制釋放及源自於海洋產物的優勢,期望在生醫載體這個領域的研究中可以有所突破,減少不必要之資源損耗,達到實質上資源的利用。
 
Keyword(s)
矽藻
多功能奈米粒子
藥物輸送
雙重影像
標靶
光熱治療
光動力治療
磁熱治療
熱控制釋放
結合治療
diatom
multifunctional nanoparticles
drug delivery
dual imaging
target
photothermal therapy
photodynamic therapy
magnetic hyperthermia therapy
thermal controlled release
synergistic therapy
 
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