Investigation of Marine Biotoxins

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Project title

Code/計畫編號

MOHW112-FDA-F114-000371

Translated Name/計畫中文名

海洋生物性毒素調查研究

Project Coordinator/計畫主持人

Tai-Yuan Chen

Funding Organization/主管機關

Food and Drug Administration, MOHW

Department/Unit

Department of Food Science

Website

https://www.grb.gov.tw/search/planDetail?id=14817223

Year

2023

Start date/計畫起

01-01-2023

Expected Completion/計畫迄

30-04-2024

Co-Investigator(s)

Deng-Fwu Hwang
Pang-Hung Hsu

Bugetid/研究經費

1781千元

ResearchField/研究領域

漁業
食品科技(農)

隨著地球暖化和氣候變遷的大環境下，使得原本只在熱帶到亞熱帶珊瑚礁魚類引起的熱帶海魚毒中毒案例(Ciguatera Fish Poisoning, CFP)有向外擴散以及中毒頻率增加之趨勢，因此重新引起世界各國對CFP的普遍重視，進行相關研究及評估增訂限量標準之必要性。海洋生物毒素是海洋中有毒藻類所產生，經由海洋中之生物如貝類、魚類等水產品攝入後蓄積於該動物體內，逾食物鏈末端的人類攝食後，即可能出現中毒症狀，嚴重者可能導致致死。本計畫目的擬針對未訂有限量標準之雪卡毒素 (Ciguatoxins, CTXs) 進行野生珊瑚礁魚種及水產品背景含量之分析進行先期研究(至少20件)，以瞭解近年該類食品中海洋生物毒性之背景值及攝食暴露風險，並與國際間海洋生物性毒素研究資料、中毒案例、最新監測數據及管理情形相互分析，召開專家會議進行研析審議(至少2場)，作為我國海洋生物毒性之政策管理精進之參考依據。Ciguatera Fish Poisoning (CFP) is an intoxication incident caused by eating fish containing ciguatoxins (CTXs), one of the most critical marine biotoxins. Given its value to human consumption as a source of protein, some commercially significant large fish groups from coral reefs may pose a hazard to food safety, harming public health. Recently, the increasing tendency of CFP incidence due to global warming and climate change has been investigated. Hence, establishing comprehensive long-term databases is crucial for detecting CTXs and CFP and appropriate management in creating a regulation limit for CTXs. To address better management of marine biotoxins, especially CTXs, the project aims to (1) collect the international CFP incidents, laws, and regulations on analytical methods for CTXs, regulation limits, monitoring, and management programs; (2) establish a dataset on CTXs from 20 coral reef fish samples; (3) organize 2 panel forum/meetings to integrate comments and suggestions by experts from government agencies (GOs) and the academe; and (4) complete an article for risk communication and a manuscript draft for the peer-review journal. Interestingly, all the generated data will initiate a proposal to come up with conclusive information on the CTXs management plan in the future.

Keyword(s)

Marine biotoxins
Ciguatera
Ciguatoxins
Monitoring data
Regulation measures
海洋生物性毒素
熱帶性海魚毒
雪卡毒素
監測數據
管理規範

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Investigation of Marine Biotoxins

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