http://scholars.ntou.edu.tw/handle/123456789/3816
標題: | Differential expression of LvHSP60 in shrimp in response to environmental stress | 作者: | Jiann-Horng Leu Wan-Ju Huang Ming-Tong Tsau Jiann-Chu Chen Li-Li Chen |
關鍵字: | HEAT-SHOCK PROTEINS;SPOT SYNDROME VIRUS;MOLECULAR CHAPERONES;PENAEUS-MONODON;INFECTION;IMMUNITY;INNATE | 公開日期: | 二月-2011 | 出版社: | ELSEVIER | 卷: | 30 | 期: | 2 | 起(迄)頁: | 576-582 | 來源出版物: | FISH & SHELLFISH IMMUNOLOGY | 摘要: | Previous studies showed that heat-shock protein 60 (HSP60) was known to function as a molecular chaperone and is an important factor in the innate immune system in mammals. However, little was known about the physiological relevance of HSP60 in marine invertebrates. This study focuses on long-term monitoring of the differential expression of LvHSP60 in shrimp Litopenaeus vannamei in response to environmental stress. The thermal aggregation assay elucidated that LvHSP60 was an effective chaperone. It also suggested that LvHSP60 may employ the cell’s intrinsic mechanism to start the immunizing process. Using quantitative real-time PCR to monitor gene expression showed that LvHSP60 was variable under different stresses including environmental stress and pathogenic infection. LvHSP60 was speculated to regulate the adaptive responses to overcome environmental stresses. In conclusion, our study proved that LvHSP60 plays an important role in the intrinsic immune system and stress responses of shrimp. |
URI: | http://scholars.ntou.edu.tw/handle/123456789/3816 | ISSN: | 1050-4648 | DOI: | 10.1016/j.fsi.2010.12.001 |
顯示於: | 水產養殖學系 海洋生物研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。