http://scholars.ntou.edu.tw/handle/123456789/10274
Title: | Development of Injectable Fucoidan and Biological Macromolecules Hybrid Hydrogels for Intra-Articular Delivery of Platelet-Rich Plasma |
Authors: | Hsien-Tsung Lu Wan-Ting Chang Min-Lang Tsai Chien-Ho Chen Wei-Yu Chen Fwu-Long Mi |
Keywords: | fucoidan;genipin;hydrogels;drug delivery;growth factors;platelet-rich plasma |
Issue Date: | 19-Apr-2019 |
Publisher: | MDPI |
Journal Volume: | 17 |
Journal Issue: | 4 |
Start page/Pages: | 236 |
Source: | Marine Drugs |
Abstract: | Platelet-rich plasma (PRP) is rich in growth factors and has commonly been utilized in the repair and regeneration of damaged articular cartilage. However, the major drawbacks of direct PRP injection are unstable biological fixation and fast or burst release of growth factors. Fucoidan is a heparinoid compound that can bind growth factors to control their release rate. Furthermore, fucoidan can re... |
URI: | http://scholars.ntou.edu.tw/handle/123456789/10274 |
ISSN: | 1660-3397 |
DOI: | 10.3390/md17040236 |
Appears in Collections: | 食品科學系 |
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