http://scholars.ntou.edu.tw/handle/123456789/9031
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chai, Huey-Jine | en_US |
dc.contributor.author | Wu, Chang-Jer | en_US |
dc.contributor.author | Yang, Shu-Han | en_US |
dc.contributor.author | Li, Tsung-Lin | en_US |
dc.contributor.author | Pan, Bonnie Sun | en_US |
dc.date.accessioned | 2020-11-20T12:05:09Z | - |
dc.date.available | 2020-11-20T12:05:09Z | - |
dc.date.issued | 2016-06 | - |
dc.identifier.issn | 1756-4646 | - |
dc.identifier.uri | http://scholars.ntou.edu.tw/handle/123456789/9031 | - |
dc.description.abstract | Benthosema pterotum is an underutilized deep-sea by-catch fish. Its protein hydrolysate (BPH) showed antioxidative activity. The BPH consisting of 13.2 mg/g of active peptides, Phe-Tyr-Tyr and Asp-Trp, significantly reduced H2O2-induced reactive oxygen species (ROS) and apoptotic cell death in human neuroblastoma SH-SY5Y cells through activation of intracellular antioxidant defence system. In Morris water-maze test, BPH was able to ameliorate memory and learning deficiency of D-galactose (D-gal)-induced neurodegenerative/ageing ICR mice. BPH-fed mice showed significantly lower levels of both D-gal-induced thiobarbituric acid reactive substances (TBARS) and endothelial nitric oxide synthase (eNOS), but higher levels of glucose-6-phosphate dehydrogenase (G6PDH) and brain-derived neurotrophy factor (BDNF) in brain of ageing mice in comparison to the control. In light of these results, BPH may be considered as a novel nutraceutical for easing the ageing and/or age-related neurodegenerative diseases. (C) 2016 Elsevier Ltd. All rights reserved. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | ELSEVIER | en_US |
dc.relation.ispartof | J FUNCT FOODS | en_US |
dc.subject | GERMINATED BROWN RICE | en_US |
dc.subject | NEUROTROPHIC FACTOR | en_US |
dc.subject | OXIDATIVE STRESS | en_US |
dc.subject | CELL-DEATH | en_US |
dc.subject | MEMORY | en_US |
dc.subject | RAT | en_US |
dc.subject | IMPAIRMENT | en_US |
dc.subject | DISEASE | en_US |
dc.subject | ACID | en_US |
dc.title | Peptides from hydrolysate of lantern fish (Benthosema pterotum) proved neuroprotective in vitro and in vivo | en_US |
dc.type | journal article | en_US |
dc.identifier.doi | 10.1016/j.jff.2016.04.009 | - |
dc.identifier.isi | WOS:000378367100042 | - |
dc.identifier.url | <Go to ISI>://WOS:000378367100042 | |
dc.relation.journalvolume | 24 | en_US |
dc.relation.pages | 438-449 | en_US |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | no fulltext | - |
item.languageiso639-1 | en_US | - |
crisitem.author.dept | College of Life Sciences | - |
crisitem.author.dept | Department of Food Science | - |
crisitem.author.dept | National Taiwan Ocean University,NTOU | - |
crisitem.author.dept | Institute of Food Safety and Risk Management | - |
crisitem.author.dept | Bachelor Degree Program in Marine Biotechnology | - |
crisitem.author.dept | Center of Excellence for the Oceans | - |
crisitem.author.dept | Doctoral Degree Program in Marine Biotechnology | - |
crisitem.author.dept | Master Program of Food Satfety Management | - |
crisitem.author.dept | National Taiwan Ocean University,NTOU | - |
crisitem.author.dept | Department of Food Science | - |
crisitem.author.dept | College of Life Sciences | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | College of Life Sciences | - |
crisitem.author.parentorg | National Taiwan Ocean University,NTOU | - |
顯示於: | 食品科學系 03 GOOD HEALTH AND WELL-BEING |
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