http://scholars.ntou.edu.tw/handle/123456789/23792| Title: | Promotion of mitochondrial biogenesis via the regulation of PARIS and PGC-1α by parkin as a mechanism of neuroprotection by carnosic acid | Authors: | Lin, Chia-Yuan Huang, Yan-Ning Fu, Ru-Huei Liao, Yu-Hsin Kuo, Tzu-Yu Tsai, Chia-Wen |
Keywords: | 6-hydroxydopamine;Carnosic acid;Mitochondrial biogenesis;PARIS;PGC-1α | Issue Date: | Jan-2021 | Publisher: | ELSEVIER | Journal Volume: | 80 | Source: | Phytomedicine : international journal of phytotherapy and phytopharmacology | Abstract: | Impairment of mitochondrial biogenesis is associated with the pathological progression of Parkinson's disease (PD). Parkin-interacting substrate (PARIS) can be ubiquitinated by parkin and prevents the repression of proliferator-activated receptor gamma coactivator-1-alpha (PGC-1α). |
URI: | http://scholars.ntou.edu.tw/handle/123456789/23792 | ISSN: | 09447113 | DOI: | 10.1016/j.phymed.2020.153369 |
| Appears in Collections: | 食品科學系 |
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